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The significant regions include all but 5 loci previously reported as genome-wide significant in large samples Supplementary Table 3. Young Gay Guys Im an open minded guy looking for some fun, lets cum together. CNVs associated with schizophrenia overlap with those associated with ASD and intellectual disability 9 as do genes with deleterious de novo mutations.

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Independently associated SNPs do not translate to well-bounded chromosomal regions. Therapeutic stasis is in large part a consequence of the fact that the pathophysiology of schizophrenia is unknown.

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Find articles by Stephanie H Witt. Find articles by Nick Craddock. Tkachev D, et al. Enrichment of Associations in Tissues and Cells Genes whose transcriptional start is nearest to the most associated SNP at each schizophrenia-associated locus were tested for enriched expression in a purified brain cell subsets obtained from mouse ribotagged lines Extended Data Extended Data Figure 1.

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